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New therapy eliminates stroke consequences Researchers at the Istituto di

Neuroscienze, part of the National Research Council CNR, have developed a new

approach to the treatment of stroke consequences. Afterwards, the motor damage

caused by a stroke can be largely remedied using a combination of neurology,

bioengineering, robot technology and hospitalization. Details were published in

"eLife". "Usually there is a perfect balance between the two halves of the

brain thanks to the nerve cord known as the corpus callosum , which enables

precise coordination between their functions," explains project manager Matteo

Caleo. The damage caused by a stroke changes this balance, with the result that

the healthy hemisphere takes command and limits the plastic potential of the

damaged tissue.

Turn off one half of the brain This new method offers a clear example of the

success that can be achieved through the interaction of bioengineering, robot

technology and clinic Matteo Caleo The procedure was successfully tested on a

paralyzed upper arm by temporarily decommissioning a small part of the healthy

half of the brain and at the same time performing physical rehabilitation using

robot technology. The result was checked using electrophysiological,

neuroanatomical and motor measurements.

"This innovative method offers a clear example of the success that can be

achieved through the interaction of bioengineering, robot technology and clinic,

" confirms Caleo. The multidisciplinary research was carried out in

collaboration with researchers from Scuola Superiore Sant'Anna and Azienda

Ospedaliera Pisana. It is part of the research project "FAS Salute 2014 -

Robotica indossabile personalizzata per la riabilitazione motoria dell 'arto

Stroke prognosis and course The course of

the disease and the chances of a cure for a stroke primarily depend on the

location and the size of the permanent brain damage. One in 5 patients dies

within the first 4 weeks. Every second person who survives a stroke remains in

need of care and severely disabled due to the damage to the brain that has

occurred. The faster the patient is treated in hospital, the greater the

chances of a complete or at least partial regression of the consequences of a

“Stroke Units” are optimally set up. They are special wards in which

diagnosis, treatment and monitoring take place after an acute

Rehabilitation is also started early here.

How long a patient stays in the hospital varies greatly from case to case. In

most cases, this is followed by rehabilitation. During this time, a team of

physiotherapists, language and occupational therapists takes care of the

patient. Another important task of rehabilitation is that those affected learn

to live with permanent impairments and to find their way in everyday life. The

patient's motivation is not to be underestimated. The more actively he

participates in the exercises and exerts himself, the greater the chances that

progress will be made. This includes treating depression that is common after a

Outpatient day care facilities are available for lighter cases. The stay in a

rehab clinic usually lasts 4 to 6 weeks. This mainly depends on the degree of


The older the patient is and the more severe the impairment from the stroke,

Younger patients and patients who show only a few

signs of failure have a better chance that the disabilities that have occurred

will largely regress. If the lost skills do not improve in the course of the

rehabilitation, the confusion or apathy persists, and bowel movements and

urination can no longer be controlled, the prognosis deteriorates. Additional

complications also affect the chances of recovery after a Causes of a

stroke Around 80% of all strokes are caused by a circulatory disorder in the

brain. One or more blood vessels are narrowed or even completely closed by

deposits on the inner walls of the arteries or by blood clots. The affected

brain regions are no longer adequately supplied with oxygen and nutrients and

are therefore damaged. Nerve cells die. Both large arteries in the brain and

small vessels inside the brain can be closed in the event of a stroke. The

extent of damage to the brain is determined by the number and size of the

arteries affected and by the presence and extent of bypass or replacement care.

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