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ANTIBIOTICS How Alexander Fleming discovered penicillin through sloppiness A

coincidence leads to Alexander Fleming developing penicillin on September 28,

1928. The era of antibiotics can begin Share: Become a Facebook fan now

Alexander Fleming caifas / Fotolia Alexander Fleming in his laboratory

discovers green . Or sloppiness. This happened in 1928 at St. Mary's Hospital

in London. In September 1928, the Scottish bacteriologist Alexander Fleming (

1881–1955) returned to his laboratory from the summer vacation. There he comes

across a petri dish with a moldy bacterial culture; Before leaving, Fleming

experimented with the Staphylococcus aureus pathogen , and the vessel remained

laboratory table. Now he is amazed to find that a tiny amount of green mold has

destroyed the bact. He manages to extract the bactericidal substance from the

mold, he calls it: penicillin. GEO Chronicle GEO CHRONICLE NO. 1 100 triumphs

of medicine Soldiers survive - thanks to penicillin Sometimes miracles take a

little longer. Fleming's publications. It was not until the Second World War

that his epoch-making discovery made a breakthrough. In animal experiments, a

team of researchers in Oxford led by Howard Florey and Ernst Chain discovered

how amazingly powerful penicillin is even against aggressive, normally deadly

bacteria. It is immediately clear to the researchers an important role in war

medicine. However, it is extremely tedious to produce the miracle substance in

sufficient quantities. The U.S. military is involved in the search for a fungal

strain that produces large amounts of The super mold is then found, it is said,

in a moldy melon in front of the institute. The quantity problem is finally

solved when the method of growing . The first major field trials took place on

the battlefields of North Africa in 1943 -. Soldiers who used to have amputated

limbs or to penicillin. From 1944, the United States increased the production

volume to such an extent that . Penicillin will soon be considered a miracle

cure In Europe, on the other hand, there is still a shortage; after the end of

the war, the life-saving agent in the destroyed cities becomes contraband - the

film "The Third Man" deals with the black market and (life- threatening)

stretched penicillin. Penicillin was considered a miracle cure in the second

half of the 20th century. It is one of the greatest innovations in medical

history and saves countless lives. Fleming's accidental discovery

revolutionized the treatment of infections that doctors had previously had

difficulty in combating or could not address at all - such as bacterial

pneumonia, scarlet fever, syphilis or tetanus. But the success also has its

downsides, the "miracle effect" of the antibiotics has s. Doctors prescribe

them too quickly and too often, and they are spread all over the world in

factory farming. Result: more and more resistant pathogens develop against

antibiotics, the weapon becomes blunt. Today, researchers are forced to develop

more and more effective variants. Fleming warned, analogously, as early as 1945

when he received the Nobel Prize: If we use this agent irresponsibly, we will

lose it again. PANDEMIC For life and death: from inside a corona clinic A team

at the University Clinic in Bonn wrestles with the virus that has changed the

world to exhaustion. During the Corona crisis, our reporters were inside this

apparatus, which deals with life and death, for weeks. And sometimes miracles.

A text by Vivian Pasquet Share: Become a Facebook fan now The enemy in the

neck - Corona reportage Daniel Etter It is after midnight when the emergency

manager and intensive care worker Stefan Lenkeit sits next to his patient in

the ambulance. He and a doctor for hours. Now it goes from the district

hospital to the Bonn University Hospital for further treatment Elisa Ferrara *

opens her eyes. She wears a shirt that is open at the back, a ventilation tube

presses air into her lungs. At the foot of the bed there are people in yellow

coats, masked with face masks, hairnets, glasses, and holding their handwritten

notes in front of their faces: Siamo in un ospedale a Bonn. Shark dolore?

Respira bene? We Do you have pain? Can you breathe well? Once Elisa Ferrara

seems to nod weakly. One of the people says, "Good morning!" In Bergamo , the

Italian fell into a coma, in Bonn she woke up to tubes weeks later. A moment

that the nurses who assisted her keep describing. A moment from a disaster

film. Elisa Ferrara, 66, and Mario Grazzini, 51, are the first seriously ill

Covid 19 patients from Hospital. The German Air Force flew them to North Rhine-

Westphalia a few days earlier. The Bonners don't know much about their Italian

patients. The only difference is that both come from Bergamo, have a family,

have been ventilated in their home country, but the to treat them further. And

that this trip is your last chance to survive. The enemy in the neck - Corona

reportage Daniel Etter There is treatment for almost every medical problem

under the roof of the Bonn University Hospital - from broken feet to brain

tumors: During the pandemic, the "maximum care provider" repeatedly takes in

Covid 19 patients from smaller hospitals "Only no Italian conditions" was the

mantra that accompanied us in the shutdown; the reports from clinics where beds

for suffocating people are missing, nurses are at the end, people without their

relatives die. That is why hospitals in Germany became the front line against

the SARS-CoV-2 virus, the new enemy. And that's why we all went into isolation

for weeks: to prevent the worst. At the University Hospital Bonn, however, they

had to expect the worst. In the clinic they call us "the world out there": the

teachers, plumbers, sales people, engineers, bakers, journalists. We who fight

our own fights with SARS-CoV-2. With loneliness, the fear of financial ruin,

the theses of conspiracy . Few of us fight a fight: the one against the virus

itself. For most, SARS-CoV-2 remains an enemy that they never encounter. While

public life was sluggish, photographer Daniel Etter and I left “the world

outside” and spent a total of . We accompanied people who keep this machine

running even in an emergency and saw the virus attack from their perspective.

Corona is a dance with the body for the intensive care physician, bad business

for the hospital buyer, and a good plan for the head of the emergency room.

Corona is an alarm tone quiz for nurses and nurses, and a love letter for the

pastor, which she reads to a patient. And for someone in this house, Corona

will be a miracle. I. Corona, a fire service One evening at the end of

February, the virus arrives in the living room of Steffen Engelhart, a hospital

hygienist. He's just been eating with his family when his phone rings. The

clinic has the first positive test for SARS-CoV-2, says the medical director. .

He convinced himself of the positive result in the laboratory of the clinic.

Minutes later, he has the infected person on the phone. A student who showed

slight symptoms in the emergency room, was smeared and had long since gone

home. He previously gave tutoring to school groups: more than 100 children.

100! Shortly before midnight, Engelhart dial. At four in the morning, the heads

of the public order and health department, the heads of the police and fire

brigade, the school, the clinic and the city director meet. Everyone knows that

you have to prevent the virus